千亿体育

醫(yi)(yi)學(xue)(xue)(xue)部坐(zuo)倚珞珈山(shan),環繞東湖(hu)(hu)水,綠樹(shu)成蔭,花香流溢。學(xue)(xue)(xue)部源于1943年成立(li)的湖(hu)(hu)北省省立(li)醫(yi)(yi)學(xue)(xue)(xue)院,現(xian)在是(shi)武(wu)漢大學(xue)(xue)(xue)六(liu)大學(xue)(xue)(xue)部之一。 學(xue)(xue)(xue)部含基礎醫(yi)(yi)學(xue)(xue)(xue)院、第(di)一臨床學(xue)(xue)(xue)院、第(di)二臨床學(xue)(xue)(xue)院、口腔醫(yi)(yi)學(xue)(xue)(xue)院、藥學(xue)(xue)(xue)院、健康學(xue)(xue)(xue)院、職業(ye)技術學(xue)(xue)(xue)院...

地址: 湖北省武漢市武昌區東湖路115號
電話: 027-68759364
中國科學院院士: 鄧子(zi)新舒紅兵
國家級教學名師: 樊明文邊(bian)專
國家杰出青年基金獲得者: 鄧子新舒紅兵章曉聯李(li)紅(hong)良卿國良
百千萬人才工程選者: 舒紅(hong)兵、黃從新章曉聯?
萬人計劃: 領軍人才: 舒紅兵唐其柱李紅良 ? ? ?
教育部新世紀優秀人才: 章曉聯、何(he)小華樂(le)江(jiang)、 于紅剛 李雁鄭芳、
胡錦躍、 黃鶴、李(li)紅(hong)良、 張 旗、 葉曉茜、 尚政軍、 郭繼華、 張(zhang)玉峰、
周海兵、 劉天罡、 王連榮、 瞿(ju)旭東、洪(hong) 葵(kui)

姓名: 樊明文

單位: 武漢大學口腔醫學院牙體牙髓科

職稱: 名譽院長、 主任醫師、教授、博導

郵箱: fmw@whuss.com

聯系電話: 027-87647443

研究方向: 1.多種新型防齲疫苗的研制,包括針對變形鏈球菌毒理因子表面蛋白和葡糖基轉移酶的靶向防齲DNA疫苗,蛋白亞單位疫苗,多肽疫苗的制備、免疫效能評價及比較。2.增強防齲疫苗粘膜免疫反應策略,包括針對粘膜抗原遞呈細胞(APC)活化的多類分子佐劑,如樹突狀細胞趨化相關分子,協同刺激相關分析,M細胞特異性靶向分子,APC模式識別受體活化激動分子等,以及相關的免疫增強效應分子機制。3.牙髓生物學研究,包括基于模式識別受體相關牙髓炎癥發生及預防和控制的分子機制,牙髓干細胞為基礎的牙髓修復再生機制。











代表性論著:

  1. Y Sun, J Han, Y Lu, X Yang, M Fan*. Biological characteristics of a cell subpopulation in tongue squamous cell carcinoma. Oral Diseases, 2012;18:169–177

  2. Xi Chen, Minquan Du, Mingwen Fan*, Jan Mulder, Marie-Charlotte Huysmans, Jo E. Frencken. Effectiveness of two new types of sealants: retention after 2 years. Clin Oral Invest, 2012;16:1443–1450

  3. X. Chen, M.Q. Du, M.W. Fan*, J. Mulder, M.C.D.N.J.M. Huysmans, J.E. Frencken. Caries-preventive effect of sealants produced with altered glass-ionomer materials, after 2 years. Dental Materials, 2012;28(5):554-60

  4. X Chen, VMJI Cuijpers, MW Fan*, JE Frencken. Validation of micro-CT against the section method regarding the assessment of marginal leakage of sealants. Australian Dental Journal, 2012; 57: 196–199

  5. Jia Rong, Guo Jihua, Fan Mingwen*. The effect of antigen size on the immunogenicity of antigen presenting cell targeted DNA vaccine. Int Immunopharmacol. 2012;12(1):21-25 (IF=2.376)

  6. Li Xiaoyan, Yang Guobin, Fan Mingwen*. Effects of Homeobox Gene Distal-less 3 on Proliferation and Odontoblastic Differentiation of Human Dental Pulp Cells. J Endod. 2012;38(11):1504-1510.

  7. G. B. Yang, X. Y. Li, G. H. Yuan, H. Liu & M. W. Fan*. Immortalization and characterization of human dental papilla cells with odontoblastic differentiation. International Endodontic Journal, 2013;46:565–572.

  8. Liulin Chen, Junming Zhu, Yuhong Li, Jie Lu, Li Gao, Huibi Xu, Mingwen Fan*, Xiangliang Yang. Enhanced Nasal Mucosal Delivery and Immunogenicity of Anti-Caries DNA Vaccine through Incorporation of Anionic Liposomes in Chitosan/DNA Complexes. PLOS ONE, 2013;8(8):e71953-e71953

  9. Xuan Hu, Xi Chen, Mingwen Fan*, Jan Mulder and Jo E. Frencken. What happens to cavitated primary teeth over time? A 3.5-year prospective cohort study in China. International Dental Journal, 2013; 63(4): 183-188

  10. Li Huang, Qing-An Xu, Chang Liu, Ming-Wen Fan*, Yu-Hong Li*. Anti-caries DNA vaccine-induced secretory immunoglobulin A antibodies inhibit formation of Streptococcus mutans biofilms in vitro. Acta Pharmacologica Sinica, 2013; 34: 239-246

  11. Yan-Hong Yan, Sheng-Cai Qi, Ling-Kai Su, Qing-An Xu*, Ming-Wen Fan*. Co-delivery of ccl19 gene enhances anti-caries DNA vaccine pCIA-P immunogenicity in mice by increasing dendritic cell migration to secondary lymphoid tissues. Acta Pharmacologica Sinica, 2013;34:432–440

  12. S. Zhang, X. Yang & M. Fan*. BioAggregate and iRoot BP Plus optimize the proliferation and mineralization ability of human dental pulp cells. International Endodontic Journal, 2013;46, 923–929

  13. Rong Jia, Xiaoxing Li, Cheng Yu, Mingwen Fan*, Jihua Guo. . Immunology Letters, 2013; 153(1–2):27-32

  14. Ling-Yun Xia, Xian-Tao Zeng, Cheng Li, Wei-Dong Leng, Ming-Wen Fan*. Association Between p53 Arg72Pro Polymorphism and the Risk of Human Papillomavirus-related Head and Neck Squamous Cell Carcinoma: A Meta-analysis. Asian Pac J Cancer Prev, 2013; 14 (10), 6127-6130

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千亿体育